Amlodipine Besylate

amlodipine

By Upsher-Smith Laboratories

What side effects are possible with this medication?

A side effect is an unwanted response to a medication when it is taken in normal doses. It  can be mild or severe, temporary or permanent, but does not occur in everyone. The following side effects have been reported by at least 1% of people taking this medication. If you develop any of these side effects (or any other side effects not listed here) or they change in intensity, speak to your doctor or pharmacist for advice on managing them and on the risks and benefits of the medication.

  • abdominal pain
  • diarrhea
  • dizziness
  • fatigue
  • flushing
  • gas
  • headache
  • heartburn
  • heart palpications
  • nausea
  • sleepiness or unusual drowsiness
  • swelling
Click here to learn about serious side effects that can potentially occur with any medication. These examples are provided for information purposes only and are not meant to be exhaustive. Always consult your doctor for sound medical advice specific to your particular medication and treatment.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online or by phone at 1-800-332-1088.

Are there any other precautions or warnings for this medication?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Heart attack and angina: On rare occasions some people, especially those with severe obstructive coronary artery disease, have developed severe angina or experienced a heart attack when starting to take this type of medication or increasing the dosage. If you experience chest pain or other signs of a heart attack, call your doctor right away or go directly to a hospital emergency room.

Liver disease: If you have liver disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Your doctor may recommend a lower dose.

Low blood pressure: This medication may cause low blood pressure. Low blood pressure is more likely to occur if you are dehydrated, are taking diuretics ("water pills"), are on a low-salt diet, or have diarrhea or vomiting. If you experience dizziness or lightheadedness, lie down until the symptoms go away and contact your doctor.

Other medications: You can use nitroglycerin while taking amlodipine. If you take nitroglycerin for angina, don't stop taking it while you are taking amlodipine.

Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.

Breast-feeding: It is not known if amlodipine passes into breast milk. Women should stop breast-feeding while they are taking this medication.

Children: The safety and effectiveness of this medication have not been established for children under 6 years of age.

Seniors: Seniors may be more sensitive to the side effects of amlodipine.

What other drugs could interact with this medication?

There may be an interaction between amlodipine and any of the following:

  • "azole" antifungals (e.g., itraconazole, ketoconazole)
  • cyclosporine
  • diltiazem
  • ritonavir
  • simvastatin

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

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The contents of this health site are for informational purposes only. Always seek the advice of your physician or other qualified healthcare provider regarding any questions you may have about a medical condition.

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