hydrocortisone enema

By Paddock Laboratories

What is this medication for?

Hydrocortisone belongs to the class of medications called corticosteroids. This medication is used to treat conditions caused by inflammation of the colon and rectum, such as certain types of ulcerative colitis, ulcerative proctitis, ulcerative proctosigmoiditis, and left-sided ulcerative colitis. It is usually used in combination with other medications.

It works within the colon and rectum to decrease inflammation. Symptoms usually improve within 3 to 5 days after starting treatment. If symptoms do not improve within 2 or 3 weeks, treatment should be stopped.

Your doctor may have suggested this medication for conditions other than those listed here. As well, some forms of this medication may not be used for all of the conditions discussed here. If you are not sure why you are using this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.

What form(s) does this medication come in?

Colocort® is available as:

  • enema
    • 100 mg per 60 mL
Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.

How should I use this medication?

The usual adult dose of hydrocortisone enema is one 60 mL enema nightly for 21 days or until remission is achieved. You should begin to feel better within 3 to 5 days of starting this medication. If treatment is continued for more than 21 days, treatment should be stopped gradually by reducing administration to every other night for 2 to 3 weeks. If your symptoms do not improve within 2 to 3 weeks, speak to your doctor.

To use the medication:

  1. Lie on your left side, shake the bottle well, and grasp the bottle at the neck where it is most rigid.
  2. Expose the lubricated tip of the bottle by removing the protective sheath.
  3. Carefully insert the lubricated tip into the rectum in the direction of the sacrum (a bone in the lower back).
  4. Slowly squeeze the container until empty.
  5. Remain in the same position for at least 30 minutes to allow distribution of the medication in the colon.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, use it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light, and keep it out of the reach of children.

Who should NOT take this medication?

Do not take this medication if you:

  • are allergic to hydrocortisone or any ingredients of the medication
  • have had an ileocolostomy and are in the immediate or early post-operative period
  • have systemic fungal infections
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The contents of this health site are for informational purposes only. Always seek the advice of your physician or other qualified healthcare provider regarding any questions you may have about a medical condition.

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