Tekturna HCT

aliskiren - hydrochlorothiazide

By Novartis

What is this medication for?

This is a combination product that contains two medications: aliskiren and hydrochlorothiazide. It is used to lower high blood pressure. It may be used when either aliskiren or hydrochlorothiazide alone is not reducing blood pressure enough, or as a first treatment for high blood pressure when it is likely that multiple medications will be needed to lower blood pressure. This medication is not intended to be the first medication used to reduce high blood pressure. It may also be used by people who have been taking both medications and wish to take a single tablet.

Aliskiren belongs to a group of medications known as direct renin inhibitors. These medications reduce blood pressure by blocking the actions of a chemical (renin) that causes blood vessels to constrict or tighten.

Hydrochlorothiazide belongs to a group of medications known as diuretics (or "water pills"). It helps control blood pressure by getting rid of excess salt and water.

People may notice an effect on their blood pressure within one week of starting the medication, with the maximum effect seen at around 4 weeks.

Your doctor may have suggested this medication for conditions other than those listed here. As well, some forms of this medication may not be used for all of the conditions discussed here. If you are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

What form(s) does this medication come in?

Tekturna HCT® is available as:

  • tablets
    • 150 mg aliskiren and 12.5 mg hydrochlorothiazide
    • 150 mg aliskiren and 25 mg hydrochlorothiazide
    • 300 mg aliskiren and 12.5 mg hydrochlorothiazide
    • 300 mg aliskiren and 25 mg hydrochlorothiazide
Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.

How should I use this medication?

The starting dose of aliskiren - hydrochlorothiazide if you have never taken these medications is 150 mg / 12.5 mg. The starting dose of aliskiren - hydrochlorothiazide if you have been taking these medications depends on the dose of the individual medications you have been taking. Aliskiren - hydrochlorothiazide is taken once daily with or without food; however, it should be taken the same way each time (i.e., if you take it with food, try to always take it with food). It should be taken at approximately the same time each day. Due to the hydrochlorothiazide, most people take this medication in the morning to avoid having to get up in the middle of the night to go to the bathroom.

Every 2 to 4 weeks, your doctor may adjust the dose of your medication, depending on how well your blood pressure is reduced and what side effects you may experience.

Other blood pressure medications may be taken with aliskiren - hydrochlorothiazide.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Who should NOT take this medication?

Do not take this medication if you:

  • are allergic to aliskiren, hydrochlorothiazide, or any of the ingredients of the medication
  • are allergic to sulfonamide medications ("sulfas")
  • are unable to urinate
  • have diabetes and are also taking ACE inhibitors (e.g., enalapril, lisinopril, ramipril) or ARBs (e.g., candesartan, losartan, telmisartan)
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The contents of this health site are for informational purposes only. Always seek the advice of your physician or other qualified healthcare provider regarding any questions you may have about a medical condition.

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